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Zázrak krev Poslušný overall mutation load and p53 mutations Srovnání směs úzkost

Biomolecules | Free Full-Text | p53's Extended Reach: The Mutant p53  Secretome
Biomolecules | Free Full-Text | p53's Extended Reach: The Mutant p53 Secretome

Pathogenesis of TP53-mutated Acute Myeloid leukemia | Laboratory of Daniel  C. Link, M.D. | Washington University in St. Louis
Pathogenesis of TP53-mutated Acute Myeloid leukemia | Laboratory of Daniel C. Link, M.D. | Washington University in St. Louis

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational  burden | Genome Medicine | Full Text
Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden | Genome Medicine | Full Text

Gain-of-function p53 protein transferred via small extracellular vesicles  promotes conversion of fibroblasts to a cancer-associated phenotype -  ScienceDirect
Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype - ScienceDirect

Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral  and Cell-Based Immunotherapies
Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies

Recent findings on molecular alterations in IDH1, TP53, and CASP9 in  gliomagenesis | Biomedical Research and Therapy
Recent findings on molecular alterations in IDH1, TP53, and CASP9 in gliomagenesis | Biomedical Research and Therapy

TP53 mutational landscape of metastatic head and neck cancer reveals  patterns of mutation selection - eBioMedicine
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine

Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway:  Cell
Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway: Cell

Homogenous TP53mut-associated tumor biology across mutation and cancer  types revealed by transcriptome analysis | Cell Death Discovery
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis | Cell Death Discovery

Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell  Lymphoma | NEJM
Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma | NEJM

Recurrent somatic mutations reveal new insights into consequences of  mutagenic processes in cancer | PLOS Computational Biology
Recurrent somatic mutations reveal new insights into consequences of mutagenic processes in cancer | PLOS Computational Biology

Omics analyses of a somatic Trp53R245W/+ breast cancer model identify  cooperating driver events activating PI3K/AKT/mTOR signaling | PNAS
Omics analyses of a somatic Trp53R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling | PNAS

Rare Mutation of TP53 Gene Leaves People at Higher Risk for Multiple  Cancers - Penn Medicine
Rare Mutation of TP53 Gene Leaves People at Higher Risk for Multiple Cancers - Penn Medicine

p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?

Clinical implications of subclonal TP53 mutations in acute myeloid leukemia  | Haematologica
Clinical implications of subclonal TP53 mutations in acute myeloid leukemia | Haematologica

Mutational processes shape the landscape of TP53 mutations in human cancer  | Nature Genetics
Mutational processes shape the landscape of TP53 mutations in human cancer | Nature Genetics

An unexpected role for p53 in regulating cancer cell–intrinsic PD-1 by  acetylation | Science Advances
An unexpected role for p53 in regulating cancer cell–intrinsic PD-1 by acetylation | Science Advances

The p53 network: cellular and systemic DNA damage responses in cancer and  aging: Trends in Genetics
The p53 network: cellular and systemic DNA damage responses in cancer and aging: Trends in Genetics

Frequency of p53 mutations in human cancers. (A) Schematic picture... |  Download Scientific Diagram
Frequency of p53 mutations in human cancers. (A) Schematic picture... | Download Scientific Diagram

Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule  Stabilizers: the Y220X Paradigm | ACS Chemical Biology
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm | ACS Chemical Biology

Development of TP53 mutations over the course of therapy for acute myeloid  leukemia - Alwash - 2021 - American Journal of Hematology - Wiley Online  Library
Development of TP53 mutations over the course of therapy for acute myeloid leukemia - Alwash - 2021 - American Journal of Hematology - Wiley Online Library

Targeting a neoantigen derived from a common TP53 mutation | Science
Targeting a neoantigen derived from a common TP53 mutation | Science

Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene

IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?
IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?

p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?

LRP1B or TP53 mutations are associated with higher tumor mutational burden  and worse survival in hepatocellular carcinoma
LRP1B or TP53 mutations are associated with higher tumor mutational burden and worse survival in hepatocellular carcinoma